Browsing by Author "Samson O. Onemu"

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    An assessment of the immune status of some stone quarry workers in Ondo state, Nigeria
    (Medicine, 2024) Samson O. Onemu; Emmanuel Ifeanyi Obeagu; Adeniyi Adewumi Popoola; Michael A. Osuntuyi; Clement N. Isibor
    Stone quarry activities in Nigeria are mostly unregulated such that the workers in these quarries are continuously exposed to the inhalation of silica dust. It has been observed that silica dust particles negatively impact the health of stone quarry workers which usually manifest as respiratory difficulties, asthma-like illnesses and other adventitious events of the lungs. The study was to evaluate the probable immunological impact of silica dust inhalation from stone crushing by workers. Blood samples were collected from consenting workers and analyzed for total white blood cells and their subsets. Absolute CD4 cells numbers were also determined. The results indicated that neutrophils and eosinophils numbers increased significantly (P < .05) and CD4 counts declined significantly (P < .001). Alteration in these proportions is a pointer to the injurious impact of silica dust on the immune system of these workers. The findings in this study should spur actions in the education of these workers on the need for the use of proper personal protection equipment and the establishment of a scheme to periodically carry out a health assessment check to identity those at most risk of developing chronic illnesses.
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    Efficacy Assessment of Some Commonly used Disinfectants against Multidrug Resistant Bacterial Isolates from a Tertiary Healthcare Facility in Benin City, Nigeria
    (Newport International Journal of Scientific and Experimental Sciences (NIJSES), 2023) Samson O. Onemu; Oluyemisi Odeyemi; Matthew Eturhobore Adu; Emmanuel Ifeanyi Obeagu
    The ever-rising numbers of multidrug resistant, MDR bacteria in healthcare facilities globally has correspondingly led to a rapid escalation in the use of disinfectants, antiseptics or biocides which reached unprecedented levels during the COVID-19 pandemic. This has also elicited grave apprehension about the development of resistance to disinfectants. This study was conducted to evaluate the effectiveness of some regularly used disinfectants in the study population. Five brands of disinfectants were obtained and diluted in sterile 300 ppm calcium carbonatenutrient broth to their respective minimum inhibitory concentrations, MICs to which were exposed broth cultures of MDR organisms for 2 min before sampling onto nutrient agar plates in replicates. Further samples were taken