Drug resistant plasmodium falciparum parasites: a review of the resistance and failure of malaria eradication
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Date
2015-12
Journal Title
Journal ISSN
Volume Title
Publisher
IJBAMR
Abstract
Malaria infection remains the leading vector borne disease in the world today. Given the increasing report of resistance or poor
responses to artemisinin based combination therapies (ACTS), the sub-Saharan African region affected by the disease might
receive a repeat of what happened during the emergence of chloroquine and sulfadoxine pyremethamine resistance. If such case
arises, the malaria control efforts in the region may be compromised and the little success gained of intervention efforts may be
eroded. Although the world has currently embraced the use of recommended artemisinin combination based therapies (ACTS) for
the treatment of uncomplicated p. malaria. Current assessment of drug susceptibility and level of circulating resistant
Plasmodium parasites is not full elucidated. Assessment of P. falciparum is thus necessary to sustain quality control programmes,
appropriate use of therapy, and health policy advice in respect of malaria management in countries where malaria is endemic.
This current paper brings out the challenge of antimalarial resistance in malaria eradication agenda.
Description
The article is available full text because it is an Open Access Article allowed by the publisher: more details:http://www.ijabmr.org/aboutus.asp
Keywords
Malaria, Antimalarial, Plasmodium, Infections, Sub Saharah Africa, Drugs, Malaria Treatment