Browsing by Author "Anthonia Onyinye Ngwoke"

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    Anaemia among pregnant women: A review in Africa
    (International Digital Organization for Scientific Research, 2023) Emmanuel Ifeanyi Obeagu; Abdi Abubakar Ali; Uche FranciscaOnwuasoanya; Anthonia Onyinye Ngwoke; Danchal Comfort Vandu; Getrude Uzoma Obeagu; Ugwu Okechukwu Paul-Chima
    Iron-deficiency anemia is the most frequent form of anemia in pregnancy and can have serious consequences for both the mother and fetus. The majority of women do not have adequate iron stores to meet the dramatic increase in requirements during the second and third trimester of pregnancy. However, there is increasing evidence that intravenous iron is more effective, provides more rapid haemoglobin correction, corrects iron stores and is better tolerated than oral iron in treating iron-deficiency anemia during pregnancy. The reported prevalence of anemia in this study is high and routine screening of pregnant women is highly recommended and further studies to explore during pregnancy is a public health problem in developed and developing countries. Pregnant women are at risk of developing anemia due to increased nutrient needs which include iron, folate and Vitamin B12 and haemo-dilution during pregnancy
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    Anaemia among pregnant women: a review in Africa
    (International Digital Organization for Scientific Research, 2023) Emmanuel Ifeanyi Obeagu; Abdi Abubakar Ali; Uche Francisca Onwuasoanya; Anthonia Onyinye Ngwoke; Danchal Comfort Vandu; Getrude Uzoma Obeagu; Ugwu Okechukwu Paul-Chima
    Iron-deficiency anemia is the most frequent form of anemia in pregnancy and can have serious consequences for both the mother and fetus. The majority of women do not have adequate iron stores to meet the dramatic increase in requirements during the second and third trimester of pregnancy. However, there is increasing evidence that intravenous iron is more effective, provides more rapid hemoglobin correction, corrects iron stores and is better tolerated than oral iron in treating iron-deficiency anemia during pregnancy. The reported prevalence of anemia in this study is high and routine screening of pregnant women is highly recommended and further studies to explore during pregnancy is a public health problem in developed and developing countries. Pregnant women are at risk of developing anemia due to increased nutrient needs which include iron, folate and Vitamin B12 and haemo-dilution during pregnancy.
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    Hematologic Support in HIV Patients: Blood Transfusion Strategies and Immunological Considerations
    (Newport International Journal of Biological and Applied Sciences (NIJBAS), 2023) Emmanuel Ifeanyi Obeagu; Getrude Uzoma Obeagu; Joseph Obiezu; Chukwujekwu Ezeonwumelu; Frances Ugonne Ogunnaya; Anthonia Onyinye Ngwoke; Obioma Raluchukwu Emeka-Obi; Okechukwu Paul-Chima Ugwu
    HIV infection presents multifaceted challenges, particularly in managing hematologic complications that significantly impact patient well-being and prognosis. Hematologic manifestations such as anemia, thrombocytopenia, and coagulopathies are prevalent in individuals living with HIV, necessitating meticulous attention and specialized care. Among the array of interventions, blood transfusions play a pivotal role in addressing these hematologic complications. However, the complexities surrounding blood transfusion strategies in the context of HIV extend beyond mere hematologic support and delve into intricate immunological considerations. This paper aims to elucidate the nuanced landscape of hematologic support in HIV patients, focusing specifically on blood transfusion strategies and their immunological implications. The review encompasses an in-depth analysis of hematologic abnormalities commonly encountered in HIV, exploring the prevalence, etiology, and clinical impact of anemia, thrombocytopenia, and coagulopathies. Additionally, it examines the indications, safety measures, and challenges associated with blood transfusion therapy in this population. Furthermore, the paper delineates the intricate interplay between blood transfusions and the immunological milieu of HIV-infected individuals. It explores the immunomodulatory effects of transfusions, potential immune activation, and the impact on disease progression, while also addressing concerns regarding all immunization and the modulation of immune responses post transfusion. By synthesizing current evidence and insights, this paper delineates the clinical outcomes, challenges, and controversies surrounding blood transfusion strategies in HIV care. It underscores the need for optimized transfusion practices tailored to the unique immunological landscape of HIV patients and highlights avenues for future research and advancements in clinical practice. In conclusion, this paper serves as a comprehensive resource elucidating hematologic support through blood transfusion strategies in HIV patients, providing a foundation for informed decision-making and paving the way for enhanced care paradigms in the management of hematologic complications in HIV.