Browsing by Author "Richard, Kambugu"

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    The effect of extract of aloe vera on ischemia-reperfusion induced Mucosa injury in the rat
    (Kampala international international: School of Health Sciences, 2014-03) Richard, Kambugu
    Aloe vera is one of the many herbal remedies used in Uganda for the treatment of a wide range of illness ranging from trauma/ wounds to infections even for cosmetic purposes. The research in to its protective role on ischemia induced gastric ulcers was aimed at establishing and confirming its reported efficacy on peptic ulcers, time of onset of action and time taken for an optimum therapeutic response. This research investigated the extent of aloe vera's protective properties which were compared with the therapeutic effects of an anti histamine ( ranitidine). The phytoextracts (mucilage) of the plant was administered to the test subjects orally by a cunnula immediately prior to ulcer induction, thereafter the subjects were sacrificed and stomach contents examined macroscopically by hand lens. The histopathological data was collected appropriately compiled and computed using a combination of textual, diagrammatic and graphical representations. This data showed that aloe vera was effective in the prevention of peptic ulcers. Using a series of statistical tools to ascertain the relevancy of the findings.