Prevalence, Patterns and Factors associated with Dyslipidemia among patients with Diabetes Mellitus attending Hoima Regional Referral Hospital
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Date
2023-05
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Kampala International University; Faculty of Cinical Medicine and Dentistry
Abstract
Background: Dyslipidemia in Sub-Saharan Africa has been on the disproportionate rise among diabetes patients across various contextual settings by its prevalence, patterns and associated factors. This study determined the prevalence, patterns and factors associated with dyslipidemia among diabetes patients attending Hoima Regional Referral Hospital (HRRH).
Method: This was a hospital-based cross-sectional study among adult 375 diabetes patients attending the diabetic outpatient clinic at Hoima Regional Referral Hospital consecutively enrolled based between October 2022 and January 2023. Data on socio-demographic, behavioural, medical history, physical examination and laboratory diagnoses were collected. Descriptive statistics were presented for all the socio-demographic, behavioural, medical history, physical examination characteristics. Prevalence of dyslipidemia was presented as a proportion of diabetes patients expressed as a percentage. Patterns of dyslipidemia were presented as a proportion of each lipid profile either singly or in combination expressed as a percentage. Bivariate analyses were conducted and variables with p<0.2 or crude odds ratios either ≥ 2 or ≤0.5 or biologically plausible were entered into multiple logistic regression model. Only factors with p<0.05 were considered statistically significant. All analyses were done using Stata version 17.
Findings: Of the 375 diabetes patients enrolled, the prevalence of dyslipidemia was 86.4% (n = 324) [95%CI: 82.5-89.5%). Of the 375 patients, the majority had abnormal TC, 69.3% (n = 260) and presented with two diagnoses of lipid profiles, 49.3% (n = 185). All diabetes patients who were overweight [100% (n = 134] or obese [100% (n = 39] at p<0.001, female patients (AOR= 2.2, 95%CI: 1.02-4.86, p <.05) diagnosed with CHD (AOR= 4.1, 95%CI: 1.51-11.07, p <.01) were more likely to have dyslipidemia although insulin treatment for diabetes compared to oral administration was protective (AOR= 0.4, 95%CI: 0.14-0.87, p <.05).
Conclusions: The prevalence of dyslipidemia at HRRH was generally high compared to other settings and was perfectly determined by overweight/obesity, female gender, CHD and oral mode of diabetes treatment.