Design of a Recombinant Hepatitis B Vaccine Based on Stably Binding HLA-I Peptides
dc.contributor.author | Ondieki, Miruka Conrad | |
dc.contributor.author | Nyaribari, Matunda Conradus | |
dc.contributor.author | Ejekwumadu, Nnamdi John | |
dc.contributor.author | Nyakang’o, Mokembo Justin | |
dc.date.accessioned | 2019-02-15T10:06:21Z | |
dc.date.available | 2019-02-15T10:06:21Z | |
dc.date.issued | 2015-02 | |
dc.description | The article is available full text. | en_US |
dc.description.abstract | The hepatitis B virus continues to infect many millions of people worldwide. There is a need to develop new vaccines against the virus. Using immunoinformatics approaches, we have predicted epitopes within the hepatitis B virus surface antigen that can be used to develop a new vaccine. The predicted epitopes were then used to construct a synthetic vaccine. The interaction between the synthetic vaccine construct and major histocompatibility complex was also predicted using bioinformatics tools. | en_US |
dc.identifier.citation | Miruka CO, Matunda NC, Ejekwumadu NJ, Mokembo JN (2015) Design of a Recombinant Hepatitis B Vaccine Based on Stably Binding HLA-I Peptides. J Biomol Res Ther 4: 120. doi: 10.4172/2167-7956.1000120 | en_US |
dc.identifier.uri | http://hdl.handle.net/20.500.12306/1596 | |
dc.language.iso | en | en_US |
dc.publisher | OMICS Publishing Group | en_US |
dc.relation.ispartofseries | Biomolecular Research & Therapeutics;Ther 4: 120 | |
dc.subject | Hepatitis B | en_US |
dc.subject | Vaccine | en_US |
dc.subject | In silico | en_US |
dc.subject | Immune informatics | en_US |
dc.subject | HLA-I Peptides | en_US |
dc.subject | Homology | en_US |
dc.title | Design of a Recombinant Hepatitis B Vaccine Based on Stably Binding HLA-I Peptides | en_US |
dc.type | Article | en_US |
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