Design of a Recombinant Hepatitis B Vaccine Based on Stably Binding HLA-I Peptides

dc.contributor.authorOndieki, Miruka Conrad
dc.contributor.authorNyaribari, Matunda Conradus
dc.contributor.authorEjekwumadu, Nnamdi John
dc.contributor.authorNyakang’o, Mokembo Justin
dc.date.accessioned2019-02-15T10:06:21Z
dc.date.available2019-02-15T10:06:21Z
dc.date.issued2015-02
dc.descriptionThe article is available full text.en_US
dc.description.abstractThe hepatitis B virus continues to infect many millions of people worldwide. There is a need to develop new vaccines against the virus. Using immunoinformatics approaches, we have predicted epitopes within the hepatitis B virus surface antigen that can be used to develop a new vaccine. The predicted epitopes were then used to construct a synthetic vaccine. The interaction between the synthetic vaccine construct and major histocompatibility complex was also predicted using bioinformatics tools.en_US
dc.identifier.citationMiruka CO, Matunda NC, Ejekwumadu NJ, Mokembo JN (2015) Design of a Recombinant Hepatitis B Vaccine Based on Stably Binding HLA-I Peptides. J Biomol Res Ther 4: 120. doi: 10.4172/2167-7956.1000120en_US
dc.identifier.urihttp://hdl.handle.net/20.500.12306/1596
dc.language.isoenen_US
dc.publisherOMICS Publishing Groupen_US
dc.relation.ispartofseriesBiomolecular Research & Therapeutics;Ther 4: 120
dc.subjectHepatitis Ben_US
dc.subjectVaccineen_US
dc.subjectIn silicoen_US
dc.subjectImmune informaticsen_US
dc.subjectHLA-I Peptidesen_US
dc.subjectHomologyen_US
dc.titleDesign of a Recombinant Hepatitis B Vaccine Based on Stably Binding HLA-I Peptidesen_US
dc.typeArticleen_US
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