Epidemiology of Coccidian Parasites in HIV Patients of Northern Uganda
dc.contributor.author | Echoru, Isaac | |
dc.contributor.author | Herman, Lule | |
dc.contributor.author | Micheni, Lisa | |
dc.contributor.author | Ajagun-Ogunleye, Mulkah O. | |
dc.contributor.author | Kalange, Muhamudu | |
dc.contributor.author | Kasozi, Keneth Iceland | |
dc.date.accessioned | 2019-02-15T12:54:24Z | |
dc.date.available | 2019-02-15T12:54:24Z | |
dc.date.issued | 2015-04 | |
dc.description | The article is available full text. | en_US |
dc.description.abstract | Aim: The epidemiology of coccidian parasites in HIV patients of sub-sahara Africa is poorly understood. This study aimed at determining the epidemiology of coccidian parasites and their associated risk factors. This was a cross sectional study carried out in Arua district in West Nile region of Northern Uganda for a period of five months. Materials and Methods: Participants in the study included HIV positive patients presenting with diarrhea. A total of 111 patients were included and classified into children, middle aged and adults. A structured questionnaire was administered, stool samples were obtained using sterile stool containers and laboratory analysis carried out using modified Ziehl-Neelsen technique (ZN). Ethical clearance was acquired and the consent of the patients was sought. Results and Discussion: Prevalence of Coccidian parasites among HIV patients was found to be 5.4% and Cryptosporidium parvum showed more prevalence than Isospora belli and Cyclospora cayatenensis i.e. (3.6%), (1.8%) and (0.0%) respectively. Most Cryptosporidium parvum infections occurred in children (13.6%) compared to adults (3.3%); with a significant relationship of (p = 0.02). The infection was higher in females (7.1%) than males (2.4%) (p = 0.19). The major risk factors associated with the disease were mainly consumption of contaminated and un-boiled water from taps and boreholes. HIV patients who took co-trimoxazole and drunk boiled water were shown to have a low prevalence of coccidian parasites of 1.9% and 2.6% respectively (p<0.05). This is because cotrimoxazole is a prophylactic drug for opportunistic infections and proper boiling of drinking water kills coccidian parasites. Conclusion and Recommendations: The study highlighted the importance and need to screen for coccidian parasites and emphasis on regular taking of prophylactic treatment as a way of controlling opportunistic infections in HIV patients. Future prevalence studies of Coccidia amongst healthy, HIV sero-negative children and adults of similar age groups in similar settings are recommended to ratify the relationship. | en_US |
dc.identifier.uri | http://hdl.handle.net/20.500.12306/1607 | |
dc.language.iso | en | en_US |
dc.publisher | SCIENCEDOMAIN international | en_US |
dc.relation.ispartofseries | British Journal of Medicine & Medical Research;7(11): 904-913 | |
dc.subject | Epidemiology of coccidia in humans | en_US |
dc.subject | Coccidiain HIV patients | en_US |
dc.subject | Coccidiarisk factors | en_US |
dc.subject | Cryptosporidium in Uganda | en_US |
dc.subject | Diarrhea in HIV patients | en_US |
dc.subject | HIV/AIDS | en_US |
dc.subject | Uganda | en_US |
dc.subject | Infectious Diseases | en_US |
dc.title | Epidemiology of Coccidian Parasites in HIV Patients of Northern Uganda | en_US |
dc.type | Article | en_US |
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