Prevalence, Severity and Factors associated with Hypoxic Ischemic Encephalopathy among Term Neonates delivered with Low APGAR Score at Hoima Regional Referral Hospital
| dc.contributor.author | Dr. Muhiadin Omar Matan | |
| dc.date.accessioned | 2026-08-11T12:54:38Z | |
| dc.date.available | 2026-08-11T12:54:38Z | |
| dc.date.issued | 2023-05 | |
| dc.description.abstract | Background: Despite neonatal encephalopathy being a significant problem worldwide and one of the major contributors to long-term neurological morbidity and mortality, there are contextual variations in its prevalence, severity, and associated factors, particularly those with low APGAR scores. This study determined the prevalence, severity, and factors associated with hypoxic ischemic-encephalopathy among term neonates delivered with Low APGAR Scores at Hoima Regional Referral Hospital. Method: This was a hospital-based cross-sectional study in the Neonatal Intensive care Unit at HRRH among 126 neonates. They were consecutively enrolled based on the hospital register of NICU between November 2022 and January 2023. Data on socio-demographic, obstetric, and clinical characteristics were collected. Descriptive statistics were presented for all characteristics considered. Prevalence of HIE was presented as a proportion of the neonates with HIE expressed as a percentage. For factors, bivariate and multivariate analyses were conducted. Only factors with p<0.05 at the multivariate stage were considered significant. The severity of HIE was presented as a proportion of the neonates with different categories of HIE among those diagnosed with HIE expressed as a percentage. All analyses were done using IM SPSS 24 Results: Of the 126 neonates with low APGAR enrolled, the prevalence of HIE was 92.1%. The risk of HIE increased significantly for neonates with meconium staining (OR= 10, 95%CI: 1.197-82.498, p= 0.033) and for neonates born to mothers who had prolonged labor, (OR=5,95%CI 1.082-27.745, p= 0.040). Of the 116 neonates with HIE, the majority had mild HIE, 44.0% followed by severe HIE, 28.5%, and moderate HIE, 27.9%. Conclusions: The prevalence of HIE among term-neonates with low APGAR scores in the 5th minute at HRRH was high. Most of the neonates delivered with low APGAR scores in the 5th minute had mild HIE. Prolonged labor and the presence of meconium staining in the amniotic fluid increased the odds of HIE. It is therefore recommended to pay close attention to women with prolonged labor and those whose amniotic fluid is stained with meconium. Early communication between the caring obstetrician and neonatology staff in case risk factors are identified. | |
| dc.identifier.uri | http://hdl.handle.net/20.500.12493/14855 | |
| dc.language.iso | en | |
| dc.publisher | Kampala International University | |
| dc.title | Prevalence, Severity and Factors associated with Hypoxic Ischemic Encephalopathy among Term Neonates delivered with Low APGAR Score at Hoima Regional Referral Hospital |
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