Browsing by Author "Hauwa Ali Buhari"

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    Advancements in Myeloid Leukemia Treatment: A Comprehensive Update
    (Journal of Biological Sciences, 2023) Hauwa Ali Buhari; Salisu, Muhammad; Emmanuel Ifeanyi Obeagu
    This comprehensive update explores the recent advancements in the treatment landscape of myeloid leukemia. Myeloid leukemia, a heterogeneous group of hematological malignancies, poses significant challenges in clinical management. This review highlights the latest therapeutic approaches, including targeted therapies, immunotherapies, and emerging treatment modalities. It discusses the impact of precision medicine, novel drug developments, and the evolving role of immunotherapy in managing myeloid leukemia. Furthermore, the abstract outlines current research trends, challenges, and future prospects, aiming to provide a concise overview for healthcare professionals and researchers involved in leukemia management.
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    Advancements in Myeloid Leukemia Treatment:A Comprehensive Update.
    (Journal of Biological Sciences, 2023) Hauwa Ali Buhari; Salisu, Muhammad; Obeagu Emmanuel Ifeanyi
    This comprehensive update explores the recent advancements in the treatment landscape of myeloid leukemia. Myeloid leukemia, a heterogeneous group of hematological malignancies, poses significant challenges in clinical management. This review highlights the latest therapeutic approaches, including targeted therapies, immunotherapies, and emerging treatment modalities. It discusses the impact of precision medicine, novel drug developments, and the evolving role of immunotherapy in managing myeloid leukemia. Furthermore, the abstract outlines current research trends, challenges, and future prospects, aiming to provide a concise overview for healthcare professionals and researchers involved in leukemia management.
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    Current Advances in the Diagnosis and Treatment of Sickle Cell Anaemia
    (Newport International Journal of Biological and Applied Sciences (NIJBAS), 2023) Hauwa Ali Buhari; Aisha Sa’ad Ahmad; Emmanuel Ifeanyi Obeagu
    Sickle cell anemia (SCA) presents a complex challenge globally due to its significant morbidity and mortality. Recent advancements in diagnostic tools and treatment modalities have revolutionized the management of this hereditary hemoglobin disorder. This paper aims to synthesize current breakthroughs in the diagnosis and treatment of sickle cell anemia. Diagnostic techniques including genetic testing, hemoglobin electrophoresis, and advanced imaging methodologies are explored, providing insights into their accuracy and clinical applicability. Moreover, novel therapeutic approaches such as gene editing, fetal hemoglobin induction, and targeted therapies are discussed for their potential in ameliorating SCA-related complications and improving patient outcomes. The paper also assesses the challenges and future prospects in the field, emphasizing the need for comprehensive strategies that encompass early detection, personalized interventions, and ongoing research efforts. Understanding these recent strides in both diagnostics and therapeutics is pivotal in enhancing the care and prognosis of individuals afflicted with sickle cell anemia.
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    Diagnosis and Treatment of Immune Heamolytic Aneamia
    (Newport International Journal of Biological and Applied Sciences (NIJBAS), 2023) Hauwa Ali Buhari; Solomon Woru Daniel; Emmanuel Ifeanyi Obeagu
    Immune hemolytic anemia (IHA) stands as a multifaceted hematologic disorder characterized by accelerated destruction of red blood cells due to immune system dysregulation. This paper aims to elucidate the nuanced landscape of IHA, focusing on its diverse diagnostic approaches and evolving treatment strategies. Diagnostic considerations encompass a range of laboratory tests, including direct and indirect Coombs tests, hemolysis markers, and autoimmune antibody panels, elucidating their roles in confirming IHA etiology and subtype classification. Additionally, advancements in imaging modalities aid in identifying underlying causative factors contributing to hemolysis. The paper further scrutinizes therapeutic interventions, spanning corticosteroids, immunosuppressive agents, and monoclonal antibodies, while also appraising emerging modalities like rituximab and splenectomy. Moreover, the role of supportive care and transfusion strategies in managing IHAassociated complications is delineated. Challenges in IHA management, including refractory cases and adverse effects of therapies, are deliberated alongside the potential of future advancements in precision medicine and targeted therapies. By assimilating the latest diagnostic methodologies and treatment paradigms, this review provides a comprehensive outlook on navigating the complexities of immune hemolytic anemia to optimize patient care and outcomes.