Antibiotic sensitivity patterns of staphylococcus aureus to methillicin in clinical samples at kid teaching Hospital.
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Date
2016-02
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kampala international international: School of Health Sciences
Abstract
Back ground: Staphylococcus aureus is a gram positive bacteria that exists on the skin as nonnal flora. It is classified as Methicillin-resistant Staphylococcus aureus (MRSA) and Methicillin-sensitive Staphylococcus aureus (MSSA) where MRSA resistant to beta lactam antibiotics. MRSA has become a predominant pathogen in the health care system causing outbreaks within the communities and hospitals. The infection risk of mortality and increases morbidity. Objective: To determine the prevalence and antibiotic sensitivity patterns of methicillin-resistant Staphylococcus aureus in clinical samples at KID-teaching hospital, Ishaka Methods: This was a cross sectional and descriptive study can Tied out for three months in the surgical ward. Patients admitted to the surgical ward with wound were included in the study after obtaining consent. Wound swabs were collected and taken to KIU-WC Microbiology laboratory where culturing, identification of S. aureus, determination of MRSA using oxacilin and antibiotics susceptibility were performed. Results: Of 114 total isolates 75(65.8%) were S.aureus isolates of which 64(85.3%) were coagulase. Of the coagulase positive S .aureus 61(81.3%) were identified to be MRSA. All the MRSA isolates were resistant to e1ythromycin, and susceptible to cloxacillin, ceftriaxone and vancomycin and intermediate sensitivity was produced reaction. Conclusion: This study showed presence of Staphylococcus aureus was among two thirds of the patients in the surgical ward and a high percentage was resistant. The prevalence of MRSA was56.1% among the Staphylococcus aureus isolates. MRSA isolates were very sensitive to vancomycin, ceftriaxone and cloxacillin
Prevalence, treatment, and gametocyte Carriage in children with malaria at Ishaka Adventist hospital
Description
A research report submitted to the school of pharmacy in Partial fulfillment of the requirement for an award of Bachelor of pharmacy degree of Kampala international University western campus.
Keywords
Pharmacy, Antibiotic sensitivity patterns, Staphylococcus aureus, Methillicin, Clinical samples, Kiu teaching Hospital