Assessment of the rational use of selected antibacterial drugs (amoxicillin, cotrimoxazole and metronidazole) in Kampala International University Teaching and Kitagata Hospitals.
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Date
2011-05
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Publisher
Kampala International University, School of Health Sciences- Western Campus
Abstract
Backgrmmd:
More than 50% of all medicines are irrationally used in the world. Rational use of medicines
(RUM) means that the right patient receives the right drug, in the right dose, for the right
duration, and at the lowest cost for him/her and the community. In a nutshell treatment must
follow the standard treatment guidelines of that area. In this case Uganda, the Uganda Clinical
Guidelines for treatment of Common Infections is used. The problem of rational use is even
most dire with antibacterial drugs, especially commonly used ones where resistance is ever
grow mg.
Purpose of study:
To assess whether amoxicillin, cotrimoxazole and metronidazole are rationally used in KlUTH
and Kitagata hospital
Methods:
Prescriptions from each hospital containing the above antimicrobial therapy were analysed to
find fi·equency of adherence to STGs by prescribers as a measure of rational use. Other
indictors of rational use such as generic name use and definitive diagnosis such as laboratory
testing were measured. Questionnaires were used to assess knowledge and frequency of use of
STGs.
Results:
From KlU-TH 7£.4•% of prescription were in accordance with STGs, KITAGATA recorded
57.1% of these drugs were prescribed in accordance with STGs. 9.£% of respondents from KIU
used Laboratory diagnosis always, from Kitagata only £% reported this.
Conclusions:
IUU-TH had higher rates of rational use of antibiotics compared to Kitagata hospital.
Cotrimoxazole had the highest rates of rational use. STGs play an important role in promoting
rational use of antibacterials.
Description
A dissertation submitted in partial fulfillment of the requirements for the award of Bachelor of pharmacy of Kampala International University.
Keywords
Antibacterial drugs, Amoxicillin, cotrimoxazole, Metronidazole