Composition analyses of some animal feeds and their effects on body weight, biochemistry Ann haematology of female wistar rats

Thumbnail Image
Journal Title
Journal ISSN
Volume Title
Kampala International University; School of Health Sciences
Nutrition is a prime contributor to good health. The six basic nutrients of the animal body include; proteins, fats, carbohydrates, water• which are macronutrients plus minerals and vitamins -micro nutrients; these must be availed in a given diet. The aim of the study was to observe the changes in physical, biochemical and hematological parameters as a result of feeding female wistar rats with 5 different animal feed type’s tor 12 weeks. Thirty female wistar rats were used in the study; separated into five equal groups (n=6). The total cholesterol, triglyceride, ASAT, ALAT, GGT, ALB, creatinine, PCV, HGB, WBCs and the deferential, RBCs, MCH. MCV, MCHC levels assayed in the blood samples; serum electrolyte levels also measured. This study was carried out in two centers: Kampala International university-Western campus Phantasy laboratory in lshaka-Bushenyi Uganda and Kabale regional hospital .TCRC laboratory in South-western Uganda. This experimental study was carried out between October 2012 and February 2013. The different needs did not significantly aftect ALAT, ASAT, and ALP; It also did not affect the electrolytes (Na+, K+, CT ) , serum total cholesterol, triglycerides and creatinine : however, a significant increase in serum urea was noted in animals in all the 5 feed groups while serum albumin levels were significantly increased in animals feel on the other 4 feed types as compared to the albumin levels of animals in control group(NUVITA®) The feeds did not significantly affect the HGB, WBC. RBC, PCV, Platelets, MCH, MCHC, MCV levels and WBC differential counts; however increase in WBC (ll.38±I.3xl03/UL) in animals ted on S&W feeds, while thrombocytopenia(PLT=385.4±l.5x!03/mm3) in animals fed on RP feeds were noted. This study result has provided clear information on the effects of 5 animal feed types on the physical, hematological, and biochemical parameters in female wistar rats. It has also clearly defined the proximate composition of the five teed types used in the study that may be used as a guide to improve animal feed formulations and avail cheaper, accessible alternative rat feeds.
A dissertation submitted to the School of Pharmacy in partial fulfillment of the requirement for the Award of the Degree of Bachelor of Pharmacy of Kampala International University
Composition analyses, Animal feeds, Body weight, biochemistry, Ann haematology, Female wistar rats