Green Nanotechnology in the Development of Antioxidant-Rich Phytotherapeutics for Metabolic Syndrome

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dc.contributor.authorZikayo Amulaga R.
dc.date.accessioned2025-06-25T15:08:02Z
dc.date.available2025-06-25T15:08:02Z
dc.date.issued2025
dc.description.abstractMetabolic syndrome (MetS), a multifactorial disorder characterized by obesity, insulin resistance, hypertension, and dyslipidemia, has emerged as a global health challenge. Conventional therapeutic approaches often come with side effects and limited long-term efficacy. Phytotherapeutics, derived from medicinal plants and rich in natural antioxidants, offer a promising alternative for managing MetS. However, issues such as poor bioavailability, instability, and low solubility limit their clinical applicability. Green nanotechnology—a sustainable approach to nanomaterial synthesis using biological resources—offers a breakthrough in enhancing the delivery and efficacy of phytochemicals. This review provides an overview of the pathophysiology of metabolic syndrome and the limitations of traditional therapies. It further explores the integration of green nanotechnology in designing nanoformulations of antioxidant-rich phytotherapeutics. Special attention is given to the mechanisms, recent advancements, types of green nanoparticles, and their synergistic potential in managing oxidative stress and metabolic dysfunction. The article also discusses safety, regulatory challenges, and prospects of green nano-based phytotherapeutics in combating metabolic syndrome.
dc.description.sponsorshipKampala International University
dc.identifier.issn1115-9790
dc.identifier.urihttp://hdl.handle.net/20.500.12493/14781
dc.language.isoen
dc.publisherResearch Output Journal of Engineering and Scientific Research
dc.titleGreen Nanotechnology in the Development of Antioxidant-Rich Phytotherapeutics for Metabolic Syndrome
dc.typeArticle
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