A Systematic Review on Acute Lymphoblastic Leukemia

dc.contributor.author	Emmanuel Ifeanyi Obeagu
dc.date.accessioned	2024-07-30T06:32:40Z
dc.date.available	2024-07-30T06:32:40Z
dc.date.issued	2022
dc.description.abstract	Acute lymphoblastic leukemia (ALL) comprises a group of lymphoid neoplasms that are morphologically and immunophenotypically similar to B and T lineage progenitors. The pathogenesis of ALL involves the abnormal proliferation and differentiation of clonal populations of lymphoid cells. Studies in pediatric populations have identified genetic syndromes that predispose to a small number of ALL cases, including Down's syndrome, Fanconi's anemia, Bloom's syndrome, ataxia-telangiectasia, and Nijmegen's breakdown syndrome. Acute lymphoblastic leukemia has been hailed as a major success story in pediatric oncology with the advent of dose-escalating chemotherapy and allogeneic SCT. However, the high risk of this disease and the significant toxicities associated with chemotherapy in adults make the results less promising. Because some studies have shown benefits of pediatric-inspired therapies, much uncertainty remains about how adults with ALL can best be managed
dc.description.sponsorship	Kampala International University, Uganda
dc.identifier.issn	2348-0319
dc.identifier.uri	http://hdl.handle.net/20.500.12493/14538
dc.language.iso	en
dc.publisher	International Journal of Innovative and Applied Research
dc.title	A Systematic Review on Acute Lymphoblastic Leukemia
dc.type	Article

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