Anemia as a Prognostic Marker for Disease Progression in HIV Infection

dc.contributor.authorEmmanuel Ifeanyi Obeagu
dc.contributor.authorGetrude Uzoma Obeagu
dc.contributor.authorEsther Ugo Alum
dc.contributor.authorOkechukwu Paul-Chima Ugwu
dc.date.accessioned2024-07-22T10:16:41Z
dc.date.available2024-07-22T10:16:41Z
dc.date.issued2023
dc.description.abstractAnemia, a prevalent hematologic manifestation in individuals living with Human Immunodeficiency Virus (HIV) infection, has garnered considerable attention as a prognostic indicator for disease progression and adverse clinical outcomes. This abstract presents a comprehensive review elucidating the intricate relationship between anemia and the progression of HIV infection, incorporating epidemiological trends, underlying pathophysiological mechanisms, clinical implications, and prognostic significance. Despite advances in antiretroviral therapy (ART), anemia remains a frequent complication in HIV infected individuals, posing substantial challenges to patient management. This paper aims to provide a nuanced understanding of anemia's role as a prognostic marker, surpassing its conventional characterization as a hematologic abnormality in the context of HIV infection. Anemia's role as a predictive marker for adverse clinical outcomes in HIV patients is explored, encompassing increased mortality rates, heightened risk of opportunistic infections, accelerated disease progression, and compromised quality of life. The review delves into its prognostic significance, shaping therapeutic decisions and prognostic assessments. This paper encapsulates the criticality of anemia as a prognostic marker for disease progression in HIV infection. Understanding its epidemiology, pathophysiological mechanisms, clinical implications, and prognostic significance is pivotal for informed clinical decision-making, prognostic assessments, and optimizing care paradigms in HIV management.
dc.description.sponsorshipKampala International University, Uganda
dc.identifier.issn2636-7254
dc.identifier.urihttp://hdl.handle.net/20.500.12493/14511
dc.language.isoen
dc.publisherJournal of Biological Sciences
dc.titleAnemia as a Prognostic Marker for Disease Progression in HIV Infection
dc.typeArticle
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