Eosinophil Dynamics in Pregnancy among Women Living with HIV: A Comprehensive Review
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Date
2024
Journal Title
Journal ISSN
Volume Title
Publisher
International Journal of Current Research in Medical Sciences
Abstract
This comprehensive review explores the intricate dynamics of eosinophils in the context of pregnancy among women living with HIV, aiming to provide a nuanced understanding of their immunoregulatory roles and potential implications for maternal-fetal health. Eosinophils, traditionally associated with allergic responses, emerge as crucial players in maintaining immune homeostasis during pregnancy. The review delves into the physiological changes of eosinophils in pregnancy, highlighting their immunomodulatory functions.In the context of HIV infection, the review examines alterations in eosinophil counts and functions, emphasizing the impact of antiretroviral therapy on these dynamics. Placental immunology and the presence of eosinophils within the placenta are explored, shedding light on their potential role in preventing infections and influencing vertical transmission of HIV. Clinical implications for both maternal and fetal health are discussed, addressing potential associations between eosinophil dysfunction and adverse pregnancy outcomes. The review concludes by identifying research gaps and proposing future directions to unravel the complexities of eosinophil dynamics in pregnant women living with HIV. Overall, this review aims to contribute valuable insights that may inform clinical practices and interventions tailored to optimize outcomes in this unique population.