Investigating the Synergistic Effects of Herbal Remedies in Treating Co-infections

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dc.contributor.authorChelimo Faith Rebecca
dc.date.accessioned2025-06-23T09:09:28Z
dc.date.available2025-06-23T09:09:28Z
dc.date.issued2025
dc.description.abstractCo-infections, defined as the simultaneous presence of multiple pathogenic organisms within a host, present complex challenges for diagnosis, treatment, and patient management. As the prevalence and detection of co-infections increase, particularly in both human and veterinary medicine, there is a growing need for therapeutic strategies capable of addressing multifactorial infections. Herbal remedies, especially those rooted in traditional systems like Traditional Chinese Medicine (TCM), offer promising multi targeted treatment alternatives due to their diverse bioactive compounds and lower toxicity profiles. This paper investigates the synergistic effects of herbal combinations against co-infections, focusing on the interactions among herbal components, their mechanisms of action, and their clinical applications. Methodologies include in vitro and in vivo testing of herbal formulas against Mycoplasma gallisepticum and Escherichia coli co-infections in poultry, with results revealing significant therapeutic potential. Challenges in standardizing and validating these treatments are discussed, alongside the implications of pharmacokinetic interactions, diagnostic ambiguity, and regulatory hurdles. The findings support further exploration of polyherbal therapy as a viable complement or alternative to conventional medicine in combating co-infections and antimicrobial resistance.
dc.description.sponsorshipKampala International University
dc.identifier.issn1115- 6198
dc.identifier.urihttp://hdl.handle.net/20.500.12493/14757
dc.language.isoen
dc.publisherResearch Invention Journal of Research in Medical Sciences
dc.titleInvestigating the Synergistic Effects of Herbal Remedies in Treating Co-infections
dc.typeArticle
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