Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12306/1596
Title: Design of a Recombinant Hepatitis B Vaccine Based on Stably Binding HLA-I Peptides
Authors: Ondieki, Miruka Conrad
Nyaribari, Matunda Conradus
Ejekwumadu, Nnamdi John
Nyakang’o, Mokembo Justin
Keywords: Hepatitis B
Vaccine
In silico
Immune informatics
HLA-I Peptides
Homology
Issue Date: Feb-2015
Publisher: OMICS Publishing Group
Citation: Miruka CO, Matunda NC, Ejekwumadu NJ, Mokembo JN (2015) Design of a Recombinant Hepatitis B Vaccine Based on Stably Binding HLA-I Peptides. J Biomol Res Ther 4: 120. doi: 10.4172/2167-7956.1000120
Series/Report no.: Biomolecular Research & Therapeutics;Ther 4: 120
Abstract: The hepatitis B virus continues to infect many millions of people worldwide. There is a need to develop new vaccines against the virus. Using immunoinformatics approaches, we have predicted epitopes within the hepatitis B virus surface antigen that can be used to develop a new vaccine. The predicted epitopes were then used to construct a synthetic vaccine. The interaction between the synthetic vaccine construct and major histocompatibility complex was also predicted using bioinformatics tools.
Description: The article is available full text.
URI: http://hdl.handle.net/20.500.12306/1596
Appears in Collections:Department of Biochemistry

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