Journal articals

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Browsing Journal articals by Author "Chidimma Maureen Chukwueze"

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    Evaluation of Knowledge, Perception and Prevalence of Helicobacter pylori Infection among Students of Enugu State University of Science and Technology: A Multi-Disciplinary Approach
    (Scholars Journal of Applied Medical Sciences, 2022) Justina Nwabunachi Ikpenwa; Christian Chinedu Aneke; Chidimma Maureen Chukwueze; Leonard C. Chukwu; Leonard C. Chukwu
    Background: The increasing prevalence of Helicobacter pylori infection globally has become a huge concern. This organism is a gram-negative bacterium that infects the lining of the stomach, causing peptic ulcer disease as well as gastric cancer. Approximately 50% of the world populations are known to be infected with Helicobacter pylori.This study evaluated the knowledge, perception as well as prevalence of Helicobacter pylori among the students of Enugu State University of Science and Technology (ESUT). A total of 1,500 who fulfilled the inclusion criteria were recruited for the study. Ethical clearance and informed consent were retrieved and a well-structured questionnaire was administered to each participant. Blood samples were collected from the participants and screened for Helicobacter pylori antibody using rapid test kits (CTK Biotech, Inc., San Diego, USA). Information obtained was analysed using SPSS version 25.0. P-values <0.05 were reflected as statistically significant. Out of the 1,500 students tested, 964 (64.3%) were positive for H. pylori. The prevalence was higher in females 896 (59.7%) as against 604 (40.4%) in males. The students within the age group of 20-24 years reported the highest prevalence. There was no statistical significance in the prevalence of Helicobacter pylori between the age groups (P=.370) and gender groups (P=.927). Based on evaluation of knowledge and perception of Helicobacter pylori among ESUT students, 1365 (91%) had heard of ulcer but only 577 (38.5%) had been diagnosed of ulcer previously. Majority of the student participants (65.7%) knew antacid as a medication for ulcer. About half the population (50.5%) perceived that ulcer is related to weight loss. 36.5% believed ulcer could bring about lack of concentration while 36.8% agreed that ulcer makes one highly irritable. Conclusion: The purpose of this work was to generate information with emphasis on the prevalence of Helicobacter pylori among the study population as well as their knowledge and perception. Information generated will help formulate public health interventions necessary to check these problems and offer evidence based preventive approach to the students of ESUT and the entire populace.
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    Evaluation of Plasma Levels of Interleukin 6 and Iron Status of Volleyball Players in a Nigerian University
    (Journal of Advances in Medical and Pharmaceutical, 2022) Emmanuel Ifeanyi Obeagu; Chinecherem Cynthia Anierobi; Gloria Chizoba Eze; Chidimma Maureen Chukwueze; Rutendo Denise Makonyonga; Nkiruka Millicent Amadi; Rifkatu Hassan
    To determine the levels of interleukin 6 (IL-6) and iron status of volleyball players in Madonna University, Elele, Rivers State, Nigeria. A total number of 80 subjects were recruited for the study, comprising of 40 subjects before playing volleyball (20 males and 20 females) and 40 subjects after playing volleyball (20 males, 20 females) from Madonna University Nigeria, Elele Campus, Rivers State, Nigeria. The data obtained from the study were presented as Mean ± SD in tables and analysed using student t-test for parametric data using SPSS version 20. The level of was set at p<0.05. The results of Table 1 showed that there was increase (p=0.003) in interleukin 6 (IL-6) after playing volleyball compared to before playing volleyball and no significant change (0.079) in iron after playing volleyball compared to before playing volleyball. Table 2 showed that there was no significant increase (p=0.164) in interleukin 6 (IL-6) of males compared to females and no significant change (p=0.589) in iron of males compared to females. Table 3 showed that there was no significant increase (p=0.921) in interleukin 6 (IL-6) of volleyball players aged 15-25 Years compared to volleyball players aged 26-35 Years and no significant change (p=0.503) in iron of volleyball players aged 15-25 Years compared to volleyball players aged 26-35 Years respectively. The study found an increase in interleukin 6 (IL-6) levels in volleyball players after games as opposed to levels before games, demonstrating that physical exercise raises interleukin 6 levels while having no impact on iron levels. significance